Karu Ramesh varma

Area: Polymorphism, Salt Screening, Crystallization Development, Solid State Characterization.

Process

Engineering and Co-crystal Design. Conducting polymorph and salt screening to identify optimal solid forms of APIs. Developing and optimizing crystallization processes to ensure desired purity, form, and particle characteristics.

Staff Scientist - Solid State Pharma Inc. - Halifax, Nova Scotia, Canada

(2025-05)

• Area: Polymorphism, Salt Screening, Crystallization Development, Solid State Characterization. Process Engineering and Co-crystal Design.
• Conducting polymorph and salt screening to identify optimal solid forms of APIs.
• Developing and optimizing crystallization processes to ensure desired purity, form, and particle characteristics.
• Performing solid-state characterization using techniques like PXRD, DSC, TGA, HPLC, NMR, GCMS, DVS, KF, and PLM/HSM.
• Supporting process scale-up and co-crystal design to improve drug properties such as solubility and stability.
• Preparing detailed technical reports documenting experimental methods, results, and conclusions.

Senior Research Associate, Discovery Department (R&D) - Sai Life Sciences Ltd. - Shameerpet, Hyderabad, Telangana

(2020-09 - 2021-08)

• Area: Multi-step synthesis (Peptide Chemistry), Medicinal Chemistry.
• Route scouting for synthesizing peptides.
• Weekly report writing.
• Guiding the M.Sc. chemists and delivering the final target compounds in time.
• Troubleshooting.
• Attending teleconferences with clients.
• Making quotations, chemical/glassware ordering, maintaining the weekly champion board, and managing the team.

Post-doctoral Research Fellow Employee - Dalhousie University - Halifax, Canada

(2023-02 - 2025-04)

Area: Medicinal Chemistry, Synthesis of peptide derivatives for enzyme inhibition studies. Project Title: Synthesis of Nocardicin Analogs. Supervisor: Prof. Stephen L Bearne.

• Propose and implement the research focused on peptide synthesis and preparation of small molecules for enzyme inhibition studies.

Post-doctoral Research Fellow - Chung-Ang University - Seoul, South Korea

(2021-09 - 2023-01)

Area: Aerobic Oxidation Catalysis, Visible Light-Driven Catalysis. Project Title: Synthesis of thermostable diazo compounds and their further transformations. Supervisor: Prof. Kyungsoo Oh.

• Develop novel methodologies via aerobic oxidations, photochemistry, electrochemistry, and flow chemistry.
• Produce well-written and thoroughly vetted research papers.
• Present research work at various conferences.
• Guide bachelor and master students.

Doctor of Philosophy (PhD) - Organic Chemistry, Carbo and Heterocycle Synthesis - Indian Institute of Technology Hyderabad (IIT-H), India (2014-07 - 2020-07)

Master of Science - Organic Chemistry - University College of Science Saifabad, Osmania University, Hyderabad, India (2011 - 2013)

Bachelor of Science - Bt. B. C (Biotechnology, Botany, Chemistry) - Sree Chaitanya Degree College, Kakatiya University, Karimnagar, India (2007 - 2010)