Marina Schneider

MSc graduate in Biochemistry with practical experience in molecular biology, protein expression, and antibody discovery gained through academic research and industry. Experienced in mammalian cell culture, cloning, and protein characterisation, with a strong interest in therapeutic antibody development.

Research Associate - LeadXpro - Villigen AG

(2026-05 - 2026-12)

• Planned and executed recombinant membrane protein expression in insect (FlashBAC) and mammalian cell systems using BacMam or transient transfection.
• Analyzed protein expression using fluorescence-based assays, FSEC, SDS-PAGE, and Western blotting.
• Optimized expression conditions to improve protein yield and quality.
• Troubleshot and optimized protein expression workflows.
• Documented experimental procedures and analyzed experimental data.

Master's Thesis | Prof. Dr. Raimund Dutzler Group - University of Zurich - Zurich

(2024-02 - 2025-03)

Project: Structural and functional characterisation of LRRC8D-containing VRAC channels in complex with synthetic nanobodies

• Optimized membrane protein expression, purification, and buffer conditions for cryo-EM studies.
• Characterized nanobody–protein interactions using HPLC-based binding assays.
• Determined the structures of three nanobody–protein complexes by cryo-EM.
• Evaluated the functional effects of nanobodies using patch-clamp electrophysiology.

Research Project | Prof. Dr. Raimund Dutzler Group - University of Zurich - Zurich

(2023-09 - 2023-11)

Project: Sybody selection for Volume-Regulated Anion Channels

• Performed sybody selection to identify binders against volume-regulated anion channels.
• Characterized sybody - protein interactions using HPLC-based binding assays.
• Conducted molecular cloning, recombinant protein purification, and buffer optimization.

Bachelor's Thesis | Prof. Dr. Martin Jinek Group - University of Zurich - Zurich

(2023-04 - 2023-06)

Project: Using archaeal splicing endonuclease to generate substrates for the human tRNA ligase complex

• Produced and purified RNA substrates for enzymatic assays
• Performed biochemical workflows and documented all procedures clearly

Assistant Nurse - Balgrist University Clinic Zurich - Zurich

(2021-02 - 2022-01)

• Supported patient care and clinical documentation in a regulated environment
• Communicated clearly while adhering to strict hygiene and safety standards

Student Assistant | Prof. O. Ulrich - University of Zurich - Zurich

(2020-11 - 2021-10)

• Supported COVID-19 testing and registration in a regulated environment.
• Handled data entry and documentation with attention to detail.

Nurse Internship - Schulthess Clinic Zurich - Zurich

(2018-09 - 2019-01)

• Supported patient care and basic medical procedures under supervision.
• Followed hygiene and safety regulations to ensure sterile working conditions.
• Developed strong organisational and teamwork skills and a disciplined working style within structured clinical workflows

Waitress - Restaurant Sihlwald

(2019 - 2019)

Ski Instructor - Schneesportschule Scuol-Ftan

(2015 - 2019)

Committee Member - Musikverein Dietlikon

(2020)

• Organise concerts and events, coordinating logistics and communication within the committee.

Master of Science - Biochemistry - University of Zurich (2023-09 - 2025-07)

Bachelor of Science - Biochemistry - University of Zurich (2019-09 - 2023-07)

Matura - Art & Music - Kantonsschule Stadelhofen (2014-08 - 2018-07)