Xifu Liang

Hello,

I am writing to apply for position as a senior scientist.

I am from China (now Danish citizen) and graduated from Shenyang College of Pharmacy with a Bachelor of Science in 1982. Then, I took a job in the then largest Chinese pharmaceutical company, Northchina Pharmaceutical Corporation (NCPC), which produces antibiotics, and had worked there in several research projects for semisynthesis of antibiotics as a process chemist for 8 years. In 1991, I was bestowed a scholarship by Chinese Education Committee and had worked with Professor Prinzbach, Universität Freiburg, on total synthesis of antibiotics for one year. Thereafter, I had worked with him as assistant for 6 years.

Professor Mikael

Bols, department of chemistry, Aarhus, offered me an opportunity to pursue my PhD. Armed with knowledge and skill I learned in Prinzbach’s group, I finished my PhD in less than 3 three years and published 12 scientific papers and 2 reviews.

Since Jan 2002 I had worked as a chemist in LEO Pharma and been involved in many different projects (more than 30 publications and patents or patent applications). Several compounds were in clinical trials. One compound I have designed, ingenol disoxate, is now in Phase 3 clinical trial.

I had worked as a chemist for over 40 years and still have passion for chemistry. II am skilled, creative, hardworking, and optimistic person with can-do attitude. I am also cooperative, and dependable. I have sound IP knowledge. Since I have worked in three countries, China, Germany, and Denmark, I also have a lot of international experience to work with different ethnic people.

LEO Pharma reorganised R and D division and decided to close the internal discovery labs, therefore, I am laid off like many other colleagues in LEO. I am now interested in trying some new challenges. I am convinced that my track record can fulfill your requirements for a Senior scientist.

Sincerely Yours

Xifu Liang

Work Experience

Aug. 2011-Jan. 2023 LEO pharma

Ballerup, Demark

Synthetic chemist (Principal Scientist)

-Drug synthesis and design (20 publications and patents or patent applications)

Jan. 2002-Jul. 2011 LEO pharma

Ballerup, Demark

Medicinal chemist (Principal Scientist)

-Drug design and synthesis (10 publications and patent or patent application

Aug. 2001-Dec. 2001 Organic Chemistry

Mikael Bols, Department of Chemistry, Aarhus University

Chemist (a transition position)

-generated compound library by using Grignard reagent

Oct. 1992-Dec.1998 Professor Horst Prinzbach, Lehrstuhl für Organische Chemie, Universität Freiburg, Germany

Assistant

-total synthesis of aminoglycoside antibiotics (3 publications).

Oct. 1991-Sep.1992 Professor Horst Prinzbach, Lehrstuhl für Organische Chemie, Universität Freiburg, Germany

Chinese scholar

-total synthesis of aminoglycoside antibiotics.

Aug. 1982-Sep.1990 Northchina Pharmaceutical Corporation (NCPC), Shijiazhuang, P. R. China

Chemist

-investigated semisyntheses of antibiotics such as clindamycin, penicillin lactamase inhibitor, cefazolin, cephalothin, cephalexin

Feb.1999-Oct. 2001 PhD, Organic Chemistry

Mikael Bols, Department of Chemistry, Aarhus University

-Chemoenzymatic syntheses of azasugars and oligo-azasugars and evaluation their biological activity and approach to solution-phase combinatorial Synthesis using Grignard reagents (13 publications)

Oct. 1978-Jul. 1982 Bachelor of Science

Major in Pharmaceutical Chemistry

Shenyang College of Pharmacy, Shenyang, P. R. China

Sep. 1990-Jul. 1991 Tongji University, Shanghai

-learning German (intensive course)