Oriane Vedrines

Scientist with 5+ years of international experience in research and clinical genomics. Expertise in cutting-edge cellular, molecular and cytogenomics biotechnologies. Experienced in implementing innovative technologies and presenting results at conferences and symposiums. Proven track record of leading complex projects, implementing innovative diagnostic technologies, and coordinating multidisciplinary clinical, regulatory, and technical teams.

Scientist – In Vitro Diagnostics at Medicover Genetics (2020-10 – 2025-07)

Implemented Optical Genome Mapping in routine cytogenetic workflows in Europe, in collaboration with Bionano US:

• Studied and optimized the limitations of the technology, including resolution, sample origin, turnaround time, and quality of results.
• Improved existing laboratory protocols and developed new SOPs for prenatal samples.
• Coordinated projects with hospitals and clinics across Germany on unique clinical cases, evaluating the added diagnostic value of the technique in prenatal settings.
• Collaborated with the US team to enhance software performance
• Interpreted structural variants in cases of rare genetic disorders
• Presented cases at the Annual Meeting of the German Society for Human Genetics.
• Led a statistical study on a large patients cohort evaluating correlations between DNA fragmentation index and sperm parameters.

Research Engineer - Cancer Biology at Research Program Unit, Helsinki University (2018-10 – 2020-01)

• Established and maintained organoid cultures from intestinal stem cells.
• Investigated neural regulation of colorectal cancer progression.
• Studied epithelial–mesenchymal transition mechanisms.

Laboratory Specialist at Woble Helsinki (2018-01 – 2018-03)

• Supervised the setup of the startup's laboratory (infrastructure, equipment, and safety compliance)
• Developed and optimized multiplex PCR protocols

Clinical Research Associate at NAMSA, Medical Research Organisation (2017-02 – 2017-08)

• Designed, planned, and supervised preclinical studies on medical devices: bone reconstruction biomaterials, pharmacokinetic monitoring of an insulin pump, and bone-cutting laser integrated into a robotic system.
• Coordinated interactions between engineers, veterinarians, and regulatory teams.

Researcher Assistant – Synthetic Biology Team at Technical Research of Finland, VTT (2016-04 – 2016-07)

• Developed modular DNA expression systems functional across multiple hosts

Master's Degree in Bioengineering, Major in Pharmacology – Polytech Clermont-Ferrand, Blaise Pascal University (2015 – 2017)

PEIP, One Year Preparatory Course to Engineering School – Pierre and Marie Curie University (2014 – 2014)

Medical Studies – Pierre and Marie Curie University (2011 – 2013)