Research co-investigator and team lead
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I have a BSc Hons in Pharmacy and obtained a PhD in molecular cancer biology within the school of Pharmacy at Queen’s University Belfast (QUB) in the UK. My independent research and management skills have progressed through the completion of my masters, PhD, and postdoctoral training. During my 15 years of research career, I have been employed in research fellow positions, during which
I have developed and maintained expertise in wide range of techniques. The majority of my research experience has been in the fields of molecular, cellular and cancer biology, with key research expertise in cancer nanomedicine and the development of novel delivery strategies for drugs and gene therapies. technically adept in a range of techniques, including cell culture (pro- and eukaryotic),
western blotting, RT-PCR, molecular cloning and flow cytometry. I am also highly proficient in the utilisation of small rodent models of disease. Regarding pharmacology, I have utilised both small molecule (e.g. receptor (ant)agonists)
and genetic (siRNA, gene overexpression, CRISPR/Cas9) methods as appropriate to manipulate cells and tissues to improve understanding of the mechanism of action of a drug/peptide
I have a BSc Hons in Pharmacy and obtained a PhD in molecular cancer biology within the school of Pharmacy at Queen’s University Belfast (QUB) in the UK. My independent research and management skills have progressed through the completion of my masters, PhD, and postdoctoral training. During my 15 years of research career, I have been employed in research fellow positions, during which
I have developed and maintained expertise in wide range of techniques. The majority of my research experience has been in the fields of molecular, cellular and cancer biology, with key research expertise in cancer nanomedicine and the development of novel delivery strategies for drugs and gene therapies. technically adept in a range of techniques, including cell culture (pro- and eukaryotic),
western blotting, RT-PCR, molecular cloning and flow cytometry. I am also highly proficient in the utilisation of small rodent models of disease. Regarding pharmacology, I have utilised both small molecule (e.g. receptor (ant)agonists)
and genetic (siRNA, gene overexpression, CRISPR/Cas9) methods as appropriate to manipulate cells and tissues to improve understanding of the mechanism of action of a drug/peptide
I am In addition to my experience in the research setting, I have gained significant industrial experience, and been involved in industrial collaborations and able to engage across these sectors in a highly productive manner. I was employed on an
Invest NI Proof of Concept grant and led this project exceptionally well on a day to-
day basis and engaged in the commercialization aspects of this project very effectively. In addition, my integral work on physiochemical characterization to the full development of a novel peptide, RALA that is used for delivery of numerous anionic cargoes has recently formed the basis of a spin-out company from QUB,
Phion Therapeutics. I was also involved in the characterisation of peptide therapeutic, ALM201. ALM201 has strong anti-angiogenic activity and is currently being assessed clinically in patients with ovarian cancer by Almac Discovery in the
UK.
During my research career, I have designed, developed, and implemented many of research projects. I was the lead scientist on a project to successfully develop and progress a novel HPV DNA vaccine from inception through to pre-clinical testing for cervical cancer.
I fulfil lab management responsibilities in my current role, being the most senior member of research staff in the lab. I provided training and mentorship to many students at both undergraduate and postgraduate level. I am involved in practical demonstration, tutorials, level 4 undergraduate pharmacy student’s final year projects and seminars within the school of pharmacy.
Lab management duties include ensuring smooth day-to-day running of the lab, maintenance of equipment, responsibility for management of stock and ordering of lab consumables, with consequent overseeing of budgets. I have planned many projects, for which I have applied for and received funding as a leading investigator for international collaboration between 4 countries of the Middle East and the UK. I am proud that I took the initiative to apply for COVID-19 grant to study drug repurposing for COVID-19.
This competitive award opened the door for further projects to be funded with total investment of £2.2 million.
As a senior researcher, I gained sufficient knowledge, management and communication skills, and my achievements have been acknowledged through several national and international awards. I have H-index of 17 and over 920
citations (Scholar). I have been named as a co- investigator on numerous successful grant applications, and hold a patent for anti-Viral therapy-2103803.9.
I have excellent written and verbal communication and presentation skills. I have communicated complex research material to audiences from diverse backgrounds,
including healthcare professionals, colleagues and collaborators, members of the public and funders.
2020Associate Fellow of the Higher Education Academy (AFHEA).2009-2012PhD in Experimental Therapeutics of Oncology “The Contribution of Reactive
Nitrogen Species to the Cytotoxicity of Nitric Oxide Generating Therapies”, School of Pharmacy, Queen’s University Belfast. Supervisor: Prof David Hirst.
2005-2006Post Grade Diploma in Clinical Pharmacology, Tripoli University, Tripoli.1998-2002B.Sc. in Pharmacy, Tripoli University, Tripoli.