Melissa Moura

Biochemistry graduate with a Master of Research (Distinction) and a strong background in molecular and cellular biology. Experienced in chromatin profiling (CUT&RUN), patient derived and 3D cancer models, and immunology-based assays, including PBMC isolation and flow cytometry. My research interests focus on gene regulation in cancer, particularly how epigenetic mechanisms influence cancer progression and the tumour microenvironment (TME), and translational research.

I am motivated to pursue doctoral training to investigate disease mechanisms and contribute to impactful biomedical research.

Research Intern - Cancer Immunology Laboratory at University of Southampton, ITRG Lab Group (2026 – Present)

• Maintained mammalian cell cultures, including neuroblastoma and rhabdomyosarcoma cell models, using sterile technique and routine cell culture practices.
• Performed experimental treatments of rhabdomyosarcoma cells with natural killer cells and analysed cellular responses using flow cytometry.
• Conducted PBMC isolation and preparation for downstream experimental work.
• Prepared and maintained cells for experimental studies and monitored cell condition throughout experiments.
• Worked both independently and collaboratively to carry out experimental procedures and meet research objectives.
• Maintained accurate experimental records and followed laboratory protocols, health and safety requirements and good laboratory practice.

Postgraduate Researcher at University of Portsmouth, School of Biological Sciences (2024-01 – 2025-01)

• Conducted antibody-based chromatin assays (CUT&RUN) under sterile conditions
• Handled Xenopus tropicalis embryos and maintained tissue cultures for genomic assays
• Supported lab demonstrations for junior students and mentored undergraduates in technique optimisation
• Maintained strict lab organisation, prepared buffers, and followed SOPs
• Documented experiments to ensure reproducibility and traceability

Undergraduate Researcher at University of Portsmouth, School of Biological Sciences (2022-01 – 2024-01)

• Developed and validated molecular tools for CUT&RUN applications
• Performed DNA library preparation and gel quantification for chromatin assays
• Presented research in internal meetings, receiving positive feedback on clarity and scientific depth

Master of Research in Biochemistry – University of Portsmouth (2024-01 – 2025-01)

BSc in Biochemistry – University of Portsmouth (2021-01 – 2024-01)