Associate scientist (Bi-specific antibody discovery), 10/2022-present
Sanofi (Kymab), Cambridge, UK
- Support an antibody discovery project to identify bi-specific or tri-specific antibodies for drug discovery to Development Candidate stage
- Participate in the formulation of bi-specific or tri-specific discovery activities including MOA, target validation, functional screening to assess molecule efficacy
- Develop and perform binding and cell-based functional assays for screening and functional assessment of antibodies
- Analyze and interpret experimental data and trouble-shooting technical issues
- Maintain accurate and up-to-date records of research
Research associate (Protein), 04/2022 – 10/2022
Nuclera Nucleics, Cambridge, UK
- Cell free protein synthesis
- Protein quantification via Bradford assays, fluorescence (microplate reader), biodrop etc.
- Production of DNA constructs (manipulation by adding flanks)
- DNA purification via kits and other methods
- Protein purification with magnetic beads
- DNA agarose gels, SDS Page, western blotting
- Various protein membrane staining, i.e., ponceau, Coomassie, histidine etc.
- Report and SOP writing
- Experiment troubleshooting
