Mass spectrometrist
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I am an enthusiastic scientist with over 20 years practical lab experience in chromatographic separation and mass spectrometry applications in small molecular studies and bioanalytical, proteomics research. I have presented data at conferences, and published in academic journals. I am capable of self-motivation as well as working as part of a team. I am flexible and can organize multiple tasks and meet deadlines.
MRC Mitochondrial Biology Unit, University of Cambridge
2010-01 to 2025-10
Research officer (Proteomics group & Mass Spectrometry Facilities)
Protein identification and quantification of highly complexity protein mixtures (Proteomes) using nano LC/MS combined with SILAC and TMT labelling technology. These techniques used to investigate protein level changes in various biological research projects.
Molecular mass measurement of intact proteins in complex protein mixtures.
Routine instrument maintenance including Orbitrap, Q-trap and associated nano and micro-LC systems.
Data interpretation using Proteome Discoverer, Max Quant, Skyline, and DIA-NN software.
Data presentations to collaborators.
MRC Human Nutrition Research, Cambridge
2008-12 to 2009-12
Method development for the analysis of Vitamin D metabolites.
Involved in NDNS (National diet and nutrition survey) project, performing measurement of the fatty acid, vitamin K, Vitamin A and D of large quantity of biological samples submitted for the project.
LC/MS for the quantification of targeted small organic molecular compounds. QA and QC for analysing organic compounds. Intra lab and inter lab comparison procedure. Handling biology hazards.
Department of Biological Sciences, Swansea University
2027-01 to 2008-11
Working on an EU project ‘Towards elimination of growth retardation in Marine Recirculating Aquaculture Systems for Turbot’(GRRAS)
Characterisation / profile of organic compounds using chromatographic and mass spectrometric methods.
PeriodTitle and nature of work/studyEPSRC national mass spectrometry service centre, Swansea University
2006-09 to2006-12
Operation and maintenance of Advion "nanomate" inlet coupled with nanospray ESI and quadrupole mass spectrometric analysis of various samples
Use of Finnegan MAT95XP, MAT900 instruments with CI, EI, FAB ionisation, both for low resolution and high-resolution accurate mass measurements.
Identification of organic compounds using GC/MS
2003-09 to 2006-09
PhD studentship in Chemistry and Biochemistry
“Quantitation of the active components of Ginkgo biloba nutrition supplements and in human urine by LC/MS”;
“Mass spectrometric analysis of changes in the murine brain phosphoproteome elicited by cyclic CMP”
Zhejiang University of Technology, Hangzhou, China
1997-09 to 2003-09
East China University of Science and Technology, Shanghai, China
1994-09 to 1997-09
Hu Qing Yu Tang Traditional Chinese Pharmaceutical Ltd., Hangzhou, China
1993-08 to 1994-08
Product testing data analysis using GC and HPLC
2003-09 to 2006-09
PhD studentship in Chemistry and Biochemistry
“Quantitation of the active components of Ginkgo biloba nutrition supplements and in human urine by LC/MS”;
“Mass spectrometric analysis of changes in the murine brain phosphoproteome elicited by cyclic CMP”
