Yevgeny Tsirulsky

Specialize in molecular biology and tissue culture. Hands-on laboratory work (in vitro, in vivo).

Experience with Quality Management System (QMS).

Experience in writing SOP and Work Instructions. Excellent interpersonal relationship. Able to work independently and in a team. Organized. Attention to details. Experienced in non-formal educational activities.

Biology and Integration scientist at Picodya (2022-06 – Present)

Laboratory Director at DiagnosTear Ltd. (2021-04 – 2022-06)

Researcher R&D, CRA at DiagnosTear Ltd. (2017-04 – 2022-06)

• Ensure that the current versions of the trial documents that are listed on the Site Initiation Report and all required trial-related materials and supplies are provided to the investigational site.
• Conduct site monitoring visits
• Site management to ensure proper adherence to protocol, source data verification and assess CRF entries.
• Develop, review and edit clinical trial related documentation including but not limited to; Case Report Forms, Informed Consent Forms
• Complete and compile all necessary research, documentation and information to gain appropriate regulatory and ethical committee approval where required.
• Contribute to development of study training materials for study team.

Researcher R&D at DiagnosTear Ltd. (2016-09 – 2022-06)

Involvement in developing an innovative Dry-Eye diagnostic test namely TeaRx (TM). TeaRx (TM), a diagnostic solution that provides a multi-parameter, objective, rapid, simple, semi-quantitative analysis of tear film in order to identify one or more underlying causes of Dry Eye Syndrome (DES).

Freelance Translator at Transcom Global Ltd. (2018-03 – 2022-06)

Translation and Proofreading of medical documents

Biology Mentor (Teacher) at The Center for Educational Technology (CET) (2014-10 – 2018-07)

Mentor in the Nachshon program, high school education in biology field

Biology and Medicine Mentor at Natali healthcare Solutions (2013-10 – 2017-02)

Mentor in the "Noar Maccabi" program, for high school students. The program sponsored by Maccabi Health Services.

Clinical Study Coordinator, Nephrology Department at Barzilai Medical Center (2015-10 – 2016-08)

Classical duties of clinical study coordinator in Nephrology Department.

• Protocol assessment for clarity and subject safety, reviews inclusion/exclusion criteria; clarifies concerns and questions with Principal Investigator and sponsor.
• Explanation and obtaining informed consent (including translation if needed), medical history and demographics.
• documentation in source file historical data, status reports, progress notes, and subject log to help ensure subject safety.
• Assistance in participant recruitment and monitors enrollment goals.
• Coordination of related facilities and equipment availability.
• Completes, audits, corrects CRFs, relays CRFs to sponsor.
• Maintenance of documents as required by FDA guidelines.
• Assistance with medical chart reviews.
• Collection, processing and shipment of specimens.

Research Assistant in the Lab of Molecular Medicine at Barzilai Medical Center (2015-10 – 2016-08)

Research academic laboratory investigating the pathophysiology of complex disease, including hypertension, diabetes mellitus and kidney disease, using experimental rodent models.

• Research laboratory management, including ordering materials for laboratory activities, planning experimental design, conducting experiments, processing and summarizing data in coordination with the lead researcher.
• Adapting research methods to the needs of the laboratory and research.
• PCR, Western blotting (WB), DNA extraction, RNA, genotyping, proteins, genotyping, work with radioactive materials and rodents (in vivo experiments).

Research Assistant at National Institute for Biotechnology in the Negev (NIBN) (2015-01 – 2015-05)

Performance of pre-clinical studies (for PK/PD evaluation), instruction of lab technician for investigated protein production, purification, analysis and subsequent in vivo experiments.

Sanitation inspector at BioCare Ltd (Israel) (2012 – 2013)

Validation of food stalls owner's compliance to the guidelines of the Ministry of Health. Generating reports and instructions for improvement.

Scientific Research Assistant at SIU School of Medicine (2011-07 – 2011-10)

I had few projects in breast cancer research laboratory, running by Prof. Sophia Ran.

• Proliferation and maintenance of hybridoma and myeloma cell lines.
• Antibodies, cells and C.M. production.
• ELISA
• Cryotomy
• Clone selection.
• Routine lab maintenance like autoclaving, buffer preparation, etc.

M.Med.Sc in molecular biology, protein engineering – Ben-Gurion University of the Negev (2012 – 2015)

High School Biology Teacher – Levinsky College (2020 – 2021)

CRA (clinical research associate) – Bioforum (2014 – 2014)

GCP (Good Clinical Practice) – Bioforum (2014 – 2014)

B.Sc in Life Sciences – Ben-Gurion University of the Negev (2008 – 2012)