Chinmay Das

Ph.D. Scholar (CSIR-Senior Research Fellow)

Talent

Mumbai, Navi MumbaiMember since August 22, 2026

Primary and 2D mammalian culturesCancer stem cell (CSC) isolation and characterizationSphere formation assaysGeneration of cancer-associated macrophages and fibroblastsHUVEC-based angiogenesis modelsCytotoxicity assays (MTT)DNA damage assessment (comet assay, γ-H2AX)Flow cytometry (FACS)

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Primary and 2D mammalian culturesCancer stem cell (CSC) isolation and characterizationSphere formation assaysGeneration of cancer-associated macrophages and fibroblastsHUVEC-based angiogenesis models

About

Cancer biologist with interdisciplinary expertise in the molecular mechanisms governing cancer initiation, progression, and therapeutic response. Built a strong scientific foundation at NISER, India, with training in protein expression, purification, and structural biology. During doctoral research at KIIT University, Bhubaneswar, developed multidisciplinary expertise using in vitro, ex vivo, in ovo, and in silico models to investigate how PARP1-driven chromatin remodeling and epigenetic changes regulate DNA repair, oncogene transcriptional activation, extracellular signaling, and tumor angiogenesis.

This research has provided broader expertise across cancer biology, including DNA repair, cancer immunology, metabolism, virus-associated cancers, tumor microenvironment, and nanotechnology-based therapeutic approaches. I am motivated to pursue postdoctoral research in cancer immunology, cancer metabolism, cancer epigenetics, chromatin biology, and extracellular vesicles to examine the molecular mechanisms that drive cancer progression and therapeutic response and to identify new ways to improve treatment outcomes.

Experience

Ph.D. (CSIR-SRF) - KIIT University, School of Biotechnology - Bhubaneswar, Odisha, India

(2022-01 - 2026-01)

Ph.D. Thesis: "Anticancer Effects of Quinacrine and Talazoparib Combination in Preclinical Models of Oral Cancer: Targeting PARP1-Mediated Chromatin Remodeling"

Supervisors: late Dr. Chanakya Nath Kundu and Dr. Tithi Parija

Project Assistant - KIIT University, School of Biotechnology - Bhubaneswar, Odisha, India

(2020-01 - 2022-01)

Project: "Talazoparib (BMN-673), a PARP inhibitor, and quinacrine synergistically induce apoptosis in buccal mucosa CSCs by inhibiting the DNA repair cascade" (ICMR-funded)