Dr. Ruchi Baghel

Scientific and Technical Oversight of implementing schemes under the Department of Health Research (DHR), drafting applications and calls for proposals, preliminary scrutiny and Proposal Reviewing, committee coordination, performance and progress evaluation of different projects, Processing of e-office files and HRD data availability and timely ministry reporting of the data. Oversight of the systematic reviews and meta-analysis, working closely with evidence synthesis teams, guideline methodologists, and statisticians to ensure methodological accuracy.

Evidence

Grading followed by guideline writing and Documentation such as Summary of Findings (SoF) frameworks, evidence-to-decision (EtD) frameworks etc.

Scientist C - Centre for Evidence-Based Guidelines, Department of Health Research (DHR), Ministry of Health and Family Welfare - Delhi

(2025-04-30)

Centre which formulates national-level evidence-based clinical practice guidelines through systematic reviews and meta-analyses. Work profile involves oversight of systematic reviews and evidence grading followed by writing and documentation.

• Ensuring that the TRC's (Technical resource hubs) in their reviews rigorously stick to the PICO decided by the GDG and also follow the SOP provided by the department
• Ensuring that the reviews capture essential information such as study design, population characteristics, intervention details, comparators, outcomes, effect measures, sample size, duration etc subject to the critical outcomes of the specific question
• Ensuring the correctness of systematic literature searches, screening strategies, PRISMA plots, characteristic tables, respective effect measures and relevancy and authenticity of forest plots and its effect measure values
• Validating the extraction and critical appraisal of data using standardized tools (e.g. Cochrane Risk of Bias Tool)
• Coordinating for revision process as and when required, before the evidence profile meeting
• Working closely with evidence synthesis teams, guideline methodologists, and statisticians to ensure methodological accuracy
• Accurately recording deliberations and rationale behind recommendations during guideline development group (GDG) meetings
• Drafting background documents pertaining to Summary of Findings (SoF) frameworks, evidence-to-decision (EtD) frameworks to support transparent decision-making and final guideline documentation
• Ensuring factual accuracy, coherence, and clarity across all documentation and annexures
• Providing technical input to other guideline-related projects or collaborations
• Facilitating expert group meetings and technical consultations

Scientist C - Human Resource Development (HRD) Division, Department of Health Research (DHR), Ministry of Health and Family Welfare - Delhi

(2024-08-25 - 2025-04-29)

HRD Division which drives India's biomedical research capacity through structured fellowship and funding programs. Work profile involves scientific and technical oversight of implementing schemes, drafting applications, proposal review, committee coordination, and performance evaluation.

• Scientific and Technical Oversight of implementing schemes under the Department of Health Research (DHR)
• Drafting applications and calls for proposals as per the scheme's guidelines to be issued or advertised by the department – a new funding scheme to cater fresh PhD's was to be made which was later on delivered as START UP GRANT with modified eligibility criteria
• Conducted initial evaluations of applications and proposals to ensure eligibility and alignment with the scheme and Human Resource Development (HRD) guidelines – as done for SUG-2024-25 scheme
• Reorganizing Technical Evaluation Committee and Approval Committee followed by their meetings for detailed proposal assessments and approvals – as done for SUG-2024-25 scheme, to find out people of relevant expertise in order to cater the wide domain of received project proposals
• Obtaining solicit performance-cum-achievement reports, annual evaluations, expert committee recommendations and timely follow-ups for smooth project completions – as done for women scientist scheme (WSS), young scientist scheme (YSS), Start-up grant scheme and support to institute scheme through emails on a daily basis
• Addressing the technical queries pertaining to extensions, fund utilization, institute or mentor change requests etc through Gov e-office file noting system
• Making end to end communications with relevant authorities and project investigators (enquirer) while maintaining due transparency and accountability
• Ensuring periodic data reporting to ministries pertaining to Outcome Output Monitoring Framework (OOMF) and progress of concerned schemes

Young Scientist-DHR - Institute of Nuclear Medicine & Allied Sciences (INMAS-DRDO) - Brig SK Mazumdar Marg, Timarpur, New Delhi, Delhi 110054

(2020-01-01 - 2024-12-31)

Metabolomics Research facility in department of Radiological nuclear and imaging science (RNAIS). Project: LCMS based plasma metabolomics of shock wave induced traumatic brain injured rats.

• Handling of Sprague Dawley (SD) Rats
• Preparing rat model of shock wave induced traumatic brain injury (TBI) followed by blood-based metabolomics and lipidomics
• Understanding, method development, validation, parameter optimization and working of UHP-LCMS (AB SCIEX Triple TOF 5600)
• Development of UHP-LCMS methods for untargeted metabolomics of urine and plasma
• Carrying out experiments and trouble-shooting for ExionLC coupled to Sciex Triple TOF 5600 (ABSciex, Singapore) in the facility
• Running of urine and plasma sample batches for metabolomics and lipidomics based profiling, followed by statistical analysis for biomarker identification

Research associate - Institute of Nuclear Medicine & Allied Sciences (INMAS-DRDO) - Brig SK Mazumdar Marg, Timarpur, New Delhi, Delhi 110054

(2017-01-01 - 2019-12-31)

NMR research centre. Project: LCMS based untargeted profiling of urine samples from radiation injury animal models. Conducted online Workshop on Metabolomics titled 'Decoding metabolomics: from profiling to biological interpretations'.

• Understanding of radiation biology in terms of C57BL6 mice, their handling, blood withdrawal followed by blood-based metabolomics
• Carrying out experiments and trouble-shooting for ExionLC coupled to Sciex Triple TOF 5600 (ABSciex, Singapore) in the facility
• Running of urine and plasma sample batches for metabolomics and lipidomics based profiling, followed by statistical analysis for biomarker identification

PhD - Biotechnology - University of Pune / CSIR-Institute of Genomics and Integrative Biology (2016-07-01)

MSc - Microbiology - B. R. Ambedkar university

BSc - Industrial Microbiology - Kurukshetra university

Intermediate - English, Physics, Chemistry, Biology, Mathematics - CBSE

Secondary High School - English, Sanskrit, Science, Maths, Social science - CBSE