Roshini Candida
M.Sc. Chemistry Graduate with Research Experience in Organic and Coordination Chemistry
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About
M.Sc. Chemistry graduate with research experience in organic and coordination chemistry, materials chemistry and biomaterials. Hands-on experience in synthesis of triazole ligands, ruthenium precursors and metal complexes, sol–gel combustion synthesis of Ce-doped rankinite, laboratory sample preparation and spectroscopic data interpretation. Experienced in operating UV–Vis and fluorescence spectroscopy for HSA interaction studies and quantitative photo physical analysis.
Experience
Research Intern - MSc Major Project - Vellore Institute of Technology - Vellore
(2025-01 - 2025-06)
Synthesis, Characterization and Photophysical Behavior of (1H-1,2,3-Triazol-4-yl) Pyridine Based Ruthenium Complexes. Final Semester project with 5-6 months duration.
- Synthesized a ruthenium metal precursor and two 1,2,3-triazole ligands, followed by preparation of four ruthenium complexes using commercially available and synthesized ruthenium precursors.
- Applied laboratory synthesis and purification techniques including reflux/heating, stirring, solvent extraction and recrystallization; developed additional column chromatography experience through general chemistry laboratory work.
- Prepared samples for ¹H NMR, ¹³C NMR, FTIR and HRMS and interpreted the resulting spectra/data; personally operated UV–Vis and fluorescence spectroscopy for data acquisition.
- Conducted UV–Vis absorption and fluorescence studies of the synthesized complexes and investigated their interactions with human serum albumin (HSA).
- Performed Stern–Volmer and Scatchard analyses and determined Stern–Volmer quenching constants (Ksv), quenching rate constants, HSA binding constants and number of binding sites.
Research Project Student - Vellore Institute of Technology - Vellore
(2024-09 - 2025-04)
Synthesis, Characterization and Biological Evaluation of Cerium-Doped Calcium Silicate for Orthopaedic Application. Part of coursework.
- Synthesized 1, 2 and 3 mol% Ce-doped rankinite by sol–gel combustion using calcium nitrate, cerium nitrate and TEOS, with citric acid as fuel, followed by combustion and calcination.
- Prepared pellets and simulated body fluid (SBF) for in-vitro bioactivity evaluation over 9 days, with periodic SBF replacement and triplicate experiments.
- Characterized samples using XRD and FTIR and interpreted phase formation, structural changes and apatite deposition following SBF immersion.
- Compared Ce concentrations and observed the most pronounced hydroxyapatite formation for the 3 mol% composition based on XRD and FTIR results.
Research Assistant - Vellore Institute of Technology - Vellore
(2024-09 - 2025-04)
PCL–Monticellite Biomaterial for Orthopaedic Applications. Additional research work.
- Synthesized monticellite and prepared PCL/PMMA/monticellite composite formulations with varying monticellite content.
- Performed FTIR characterization to examine functional groups and polymer–ceramic interactions across the prepared formulations.
Research Intern - IIT Madras – International Center for Clean Water - Chennai
(2022-09 - 2022-10)
Research internship focused on water sample analysis and quality assurance procedures.
- Conducted chemical and elemental analysis of 30+ water samples using titration and ion-selective electrode techniques.
- Prepared calibration standards and supported instrument accuracy and QA/QC procedures.
- Analyzed experimental data using MS Excel, compiled technical reports and presented findings in the context of environmental safety benchmarks.
Education
M.Sc. - Chemistry - Vellore Institute of Technology (VIT) (2024-07 - 2026-06)
B.Sc. - Chemistry - Stella Maris College (2020-06 - 2023-05)
