Srinivasarao Yadlapalli

Performance-driven pharmaceutical operations leader with 27+ years of expertise in large-scale API manufacturing and site leadership across Natco, Dr. Reddy's, Orchid Pharma, Mylan, Hetero Labs, Aurobindo & Cohance. Proven expertise in site leadership, full P&L ownership, and global regulatory compliance with a strong track record of successful inspections by USFDA, EDQM, WHO, COFEPRIS, PMDA & KFDA.

Strong capability in strategic planning, Capex/Opex optimization, production efficiency, operational excellence and capacity expansion across large-scale commercial API facilities. Proven experience in technology transfer, process scale-up, and commercialization of APIs while ensuring quality, cost, and timeline objectives.

GM – Manufacturing and Operations - Cadchem Laboratories Ltd

(2026-01)

• Responsible for leading and managing the entire production operations of API manufacturing across multiple pharma blocks, pilot plant, and SRP facilities.

DGM – Production Head - Cohance Life Sciences (RA Chem Pharma)

(2024-02 - 2025-05)

Re-appointed to lead manufacturing excellence, ensure operational continuity, and deliver on strategic business goals. Total Association: 2 Years 4 Months

• Headed multi-product API manufacturing at a 500 KL facility with 105 reactors and 9 clean rooms.
• Owned end-to-end site operations covering Production, PPIC, Engineering, Utilities, and EHS.
• Led technology transfer, scale-up, validation, capacity enhancement & cost optimization initiatives.
• Strengthened audit readiness, supporting USFDA & EDQM inspections.
• Drove operational excellence and people development through Kaizen/5S and strong leadership.

Sr. GM – Mfg. & Operations - Cohance Life Sciences (RA Chem Pharma)

(2020-06 - 2021-05)

• Headed multi-product API manufacturing at a 500 KL facility with 105 reactors and 9 clean rooms.
• Owned end-to-end site operations covering Production, PPIC, Engineering, Utilities, and EHS.
• Led technology transfer, scale-up, validation, capacity enhancement & cost optimization initiatives.
• Strengthened audit readiness, supporting USFDA & EDQM inspections.
• Drove operational excellence and people development through Kaizen/5S and strong leadership.

GM – Operations - Enaltec Pharma., Indore

(2023-06 - 2024-02)

Role expanded from production leadership to overall site operations. Total Association: 1 Year

• End-to-end responsibility for site operations, P&L, and cost control.
• Led technology transfer, capacity enhancement, and yield improvement.
• Strengthened team capability and shop-floor discipline.

GM – Production - Enaltec Pharma., Indore

(2021-12 - 2022-03)

• End-to-end responsibility for site operations, P&L, and cost control.
• Led technology transfer, capacity enhancement, and yield improvement.
• Strengthened team capability and shop-floor discipline.

AGM – Production - Aurobindo Pharma Ltd, Vizag

(2019-03 - 2020-05)

• Oversaw 5 multi-production blocks & 1 Int. Block in a USFDA approved facility with 4 clean rooms.
• Managed Valsartan & Olmesartan blocks, leading end-to-end API manufacturing operations.
• Ensured GMP, EHS, and regulatory compliance across all activities.
• Achieved production targets through process optimization, yield improvement, and cost control.

AGM – Production - Hetero Labs., Nakkapalli

(2017-08 - 2019-03)

• Managed 3 API production blocks and 48 reactors with 470 KL total capacity.
• Oversaw monthly output of 45 tons (Efavirenz – 30 tons, Tenofovir – 15 tons) in a USFDA-approved facility
• Directed end-to-end manufacturing operations ensuring GMP, EHS, and regulatory compliance.
• Led process optimization, yield improvement, and cost-control initiatives.

Sr. Manager – Production - Mylan Laboratories Ltd.

(2010-04 - 2017-08)

• Oversaw 4 multi-product API blocks and a pilot plant in a USFDA-approved facility.
• Managed production of 18 APIs, ensuring GMP, EHS, and quality compliance.
• Led 12 successful scale-ups and multiple technology transfer projects.
• Prepared and executed production schedules, achieving OTIF delivery targets.
• Directed capacity enhancement initiatives and maintained budget yields with strict cost control.

Deputy Manager – Production - Orchid Pharma., Aurangabad

(2008-04 - 2010-04)

• Managed a Semi-DCS API block with 28 reactors (168 KL) and 2 clean rooms.
• Planned and executed production schedules; ensured GMP, safety, and regulatory compliance.
• Led scale-up, technology transfer, and validation of new processes.

Assistant Manager – Production (Pilot Plant) - Ind-Swift Laboratories Ltd

(2005-10 - 2008-04)

• Managed pilot plant operations, overseeing scale-up and exhibit batches.
• Coordinated with R&D and QA for smooth technology transfer; maintained cGMP and documentation compliance.

Production Officer - Dr. Reddy's Laboratories Ltd

(1999-09 - 2004-03)

• Executed API batch operations per SOPs and cGMP; ensured GMP, safety, yield, and schedule adherence.

Production Chemist - Natco Pharma Ltd

(1997-10 - 1999-09)

API manufacturing & operations - Glenmark

(2004-03 - 2005-10)

Gained additional exposure to API production & quality systems.

API manufacturing & operations - RL Fine Chem

(2022-09 - 2023-05)

Gained additional exposure to API production & quality systems.

M.Sc. - Chemistry - Annamalai University, Chidambaram

B.Sc. - Mathematics, Physics & Chemistry - J.K.C. College, Nagarjuna University, Guntur