Research Associate – I - Zoological Survey of India (ZSI) - Kolkata
(2025-06)
NMHS-LG Funded Project
- Led Oxford Nanopore-based NGS workflows for faunal diversity mapping across Indian Himalayan regions, integrating field sample collection with end-to-end computational analysis.
- Designed and implemented reproducible DNA barcoding and NGS analysis pipelines, improving species identification throughput and analytical consistency.
- Executed systematic data QC, sequence analysis, and structured reporting protocols to ensure high-quality downstream interpretation and regulatory compliance.
- Delivered actionable biodiversity insights by integrating multi-source field and sequencing data, directly supporting conservation decision-making.
Project Research Scientist – I (Cancer Genomics) - Homi Bhabha Cancer Hospital & Research Centre - Muzaffarpur
(2024-08 - 2025-02)
ICMR-Funded Project
- Architected and deployed end-to-end NGS diagnostic pipelines for Head and Neck Cancer datasets, covering FASTQ ingestion through clinical-ready reporting.
- Performed transcriptomic profiling and biomarker-oriented downstream analysis, enabling precision medicine insights and supporting clinical interpretation.
- Partnered with clinical oncologists and wet-lab teams to co-design experimental frameworks, optimize QC thresholds, and align analytical outputs with diagnostic workflows.
- Produced clinically actionable analytical reports that directly bridged bioinformatics outputs with medical decision-making processes.
Research Associate - Department of Zoology, University of Delhi - New Delhi
(2016-12 - 2019-07)
DST-SERB Funded Project
- Developed automated high-throughput pipelines for transcriptomics and metagenomics analysis in avian model systems, enabling systematic multi-condition comparisons.
- Conducted large-scale differential gene expression (DGE) and pathway enrichment analyses, yielding mechanistic insights into seasonal reproductive and metabolic biology.
- Integrated multi-omics datasets (transcriptomics + microbiome) to construct systems-level biological interpretations of host-microbe interactions.
- Co-authored 6+ peer-reviewed publications in high-impact journals (Scientific Reports, Molecular & Cellular Endocrinology, Microbiological Research).
Doctoral Research – PhD, Biotechnology - National Centre for Cell Science (NCCS) - Pune
(2019-08 - 2024-07)
Thesis: Role of SH3PXD2B in Breast Cancer Lung Metastasis • Supervisor: Dr. Shailza Singh
- Executed multi-omics analysis integrating bulk RNA-seq, scRNA-seq, and functional assay data to elucidate metastatic mechanisms in breast cancer.
- Performed comprehensive single-cell RNA-seq analysis using Seurat: unsupervised clustering, pseudotime trajectory inference, and differentially expressed gene (DEG) identification across tumor microenvironment cell populations.
- Identified key molecular drivers of epithelial–mesenchymal transition (EMT) and characterized SH3PXD2B as a novel regulator of breast cancer lung colonization.
- Developed modular, reproducible bioinformatics workflows for high-throughput omics data processing, annotated for reuse across collaborative projects.
- Validated computational predictions through independent in vitro (MCF-7, MDA-MB-231, MDA-MB-468, A549, NCIH1975 cell lines) and in vivo mouse model experiments.
- Presented doctoral findings at multiple national and international conferences; received Best Poster Award at PSI-IICB 2022 (Molecular Omics category).
