Syed Ibrahim

Dynamic and results-driven professional targeting a senior-level position in pharmaceutical research and development focused on driving innovation, process optimization, and operational excellence. Leveraging extensive expertise in API synthesis and process enhancement to deliver cost-effective, high-quality solutions while contributing to organizational growth and staying aligned with evolving technological advancements in a dynamic and progressive environment.

Manager - CDYMAX (India) Pharma, Bangalore - Bangalore

(2024-04)

• Leading process development activities for antiretroviral and oncology APIs.
• Managing and mentoring R&D teams to deliver efficient process development, optimization, and technology transfer.
• Successfully developed and transferred over 18 APIs including major oncology molecules such as Sunitinib Malate, Nilotinib HCl, Abacavir, TDF, Efavirenz, Dolutegravir, Erlotinib, Nintedanib, Capecitabine, Pazopanib, Palbociclib, Dasatinib, Ibrutinib, Olaparib, Ribociclib, Imatinib, Alectinib HCl, and Venetoclax.
• Currently spearheading process development for Alectinib HCl, Venetoclax, and Apalutamide.
• In-charge for preparing comprehensive documentation including Batch Manufacturing Records (BMR), Manufacturing Formula Records (MFR), Technology Transfer Documents (TTD), CAPA, investigation reports, and cost analyses.

Deputy Manager - CDYMAX (India) Pharma, Bangalore - Bangalore

(2022-04 - 2024-03)

Assistant Manager - CDYMAX (India) Pharma, Bangalore - Bangalore

(2020-04 - 2022-03)

Sr. Executive - CDYMAX (India) Pharma, Bangalore - Bangalore

(2018-04 - 2020-03)

Executive - CDYMAX (India) Pharma, Bangalore - Bangalore

(2015-06 - 2018-03)

Senior Scientist - Sequent Scientific Ltd. - Bangalore & Mangalore

(2011-10 - 2015-06)

• Developed and optimized synthetic processes for various penems, veterinary drugs, and human pharmaceuticals.
• Successfully implemented commercial-scale processes for Ertapenem Sodium, Meropenem, Imipenem, Nifuroxazide, Firocoxib, and others.
• Expert in multi-step synthesis, hydrogenation techniques under air-sensitive conditions, and purification methods such as column chromatography, recrystallization, and high vacuum distillation.
• Led impurity isolation and characterization using advanced analytical techniques (NMR, Mass Spec, LCMS, HPLC).
• Supervised and guided junior scientists while coordinating scale-up trials and cost management.
• Applied microwave-assisted synthesis for stereospecific compounds enhancing impurity profiling.

Scientist - Sequent Scientific Ltd. - Bangalore & Mangalore

(2010-11 - 2011-10)

Research Executive - Orchid Chemicals and Pharmaceuticals Ltd. - Chennai

(2006-06 - 2010-11)

• Engaged in process development and optimization for beta-lactams, cephalosporins, penems, and penicillin derivatives.
• Developed cost-effective and scalable processes for cephalosporins and Ceftaroline, including side chain modifications for Ceftarolin Fosamil acetate.
• Successfully developed synthetic routes for Panipenem and managed CRAMS projects.
• Conducted impurity enrichment and structural elucidation through NMR, mass spectrometry, LCMS, and HPLC.

Ph.D. Candidate - Organic Chemistry - CMR University (2023)

M.Sc. - Chemistry - Saraswathi Narayanan College, Madurai Kamaraj University (2006)

B.Sc. - Chemistry - Thiagarajar College, Madurai Kamaraj University (2004)