Avishek Mojumdar

Downstream process development scientist focused on laboratory study execution and data generation — chromatography (affinity, ion-exchange, size-exclusion) and filtration (TFF, NFF) development studies, high-throughput purification screening, and dynamic binding capacity characterization — with in-process analytics by SoloVPE and HPLC and data analysis in JMP. Strong technical documentation and authoring. Seeking a Downstream Process Development Associate Scientist role generating high-quality data to develop and characterize viral vector purification processes.

Downstream Bioprocessing Associate II - WuXi Biologics - Cranbury, NJ

(2026-02)

• Analyze in-process and historical batch data in JMP to characterize process consistency and step recovery (90s–high-90s per step, ~80% overall) and support disposition; return floor observations to development and tech transfer
• Quantify in-process protein concentration by SoloVPE variable-pathlength (slope) spectroscopy, generating analytical data for pool-criteria decisions
• Operate ÄKTA Process chromatography across affinity (Protein A), ion-exchange, and hydrophobic-interaction steps in a GMP clinical environment, resolving method phases over defined column volumes to meet purity and pool-criteria targets
• Conduct UF/DF on Sartoflow and Watson-Marlow TFF systems (Millipore Pellicon cassettes), regulating transmembrane pressure via in-line PendoTech monitoring to achieve target concentration and buffer exchange
• Perform normal flow filtration — viral filtration (Millipore Viresolve, Planova) and depth filtration for clarification and bioburden reduction — and low-pH viral inactivation per validated parameters
• Prepare chromatography columns, buffers, and single-use consumables for production runs; interface with Process Development, QA, and QC to execute PD-developed processes at scale

DS Biopharmaceutical Manufacturing Associate I (Contract) - Sanofi S.A. - Pearl River, NY

(2025-12 - 2026-02)

• Cross-trained across ÄKTA chromatography (IEX, HIC), tank assembly, buffer/reagent preparation, and CIP/SIP on a commercial GMP downstream line, supporting senior operators to hold batch schedule
• Executed in-process sampling and GMP batch documentation per site SOPs, reinforcing data integrity

R&D Downstream Drug Substance Development Intern - GlaxoSmithKline - King of Prussia, PA

(2024-06 - 2024-08)

• Executed high-throughput purification screening studies of Protein A resins, generating dynamic binding capacity (DBC) datasets across load and residence-time conditions to inform resin selection and platform scale-up
• Trained in ÄKTA and HPLC method development; built and ran chromatography methods to support screening studies and product-quality characterization
• Designed and executed orthogonal separation experiments (affinity, SEC, IEX, HIC) on ÄKTA Avant and Pure at pilot scale, generating comparative purification data
• Generated mAb product-quality data by SEC-HPLC (aggregate/HMW species) and RP-HPLC (polysorbate-80 degradation) on Agilent 1260, and protein concentration by SoloVPE; interpreted results to support purity and stability assessment
• Documented all experiments, methods, and results in ELN under GLP; gained cross-functional exposure to upstream and harvest operations for end-to-end process context

Bachelor of Engineering - Chemical and Molecular Engineering - Stony Brook University (2021-08 - 2025-05)

Master's of Science - Engineering Management - Northeastern University (2026-09 - 2028-03)