Bliss Singhal

I am a freshman at the University of Pennsylvania with major in Computer Science.

RESEARCH INTERN: ANTIBACTERIAL PEPTIDE DESIGN FOR LTAS INHIBITION June 2023 – June 2024

• Utilized Machine Learning (ML) to engineer highly specialized AMPs to effectively neutralize LtaS, a crucial enzyme found in gram-positive bacteria responsible for severe diseases, including bacterial meningitis and pneumonia.

• Developed a comprehensive framework for scalable seizure prediction that predicted seizures hours before seizure onset, while previous research’s prediction time was at most 15 min. Utilized MNE library for signal processing techniques, including bandpass filtering and independent component analysis (ICA). Applied deep learning models using TensorFlow, including CNNs, RNNs, and LSTMs, to enhance prediction accuracy by 90% within 2 hours. 

• Conducted advanced research in clustering and visualization of DNA electrical signals with UW Electrical and Computer Science Engineering faculty, using AI to analyze complex datasets. Implemented and visualized machine learning clustering algorithms, including HDBSCAN, DBSCAN, agglomerative clustering, K-means clustering, and DMODX, to effectively separate representative data from noise.

• Developed a novel metastatic cancer detection system using the genetic algorithm, decision trees, PCA, logistic regression, and k-nearest neighbors with a 70% accuracy over manual detection for robust predictive modeling. Employed Python libraries such as Pandas, Numpy, Matplotlib, Seaborn, Sklearn, Poetry, and Imageio for efficient data processing and visualization. 

EDUCATION

University of Pennsylvania, School of Engineering and Applied Science, Philadelphia, PA Aug. 2024 – June 2028

Major: Computer Science