50% of professionals earn between $44,000 - $75,000 USD
The median salary is $53,000
The average salary for a Substance in United States is USD 65,783 - USD 92,905 per year in 2026. The median salary is USD 61,500 per year, based on 2,918 active job listings.
The cities with the most Substance job opportunities in United States are San Diego, Baltimore, Los Angeles, Corcoran, Fort Pierce. San Diego leads with 49 job openings.
Leading employers for Substance roles in United States include Comprehensive Treatment Centers, Gateway Foundation, New Season, AVENUES RECOVERY CENTER, IDS Health, Inc.
Explore 2,918 Substance job listings in United States on BeBee, or check our salary calculator for a personalized estimate.