Shaima Belhechmi

Senior biomarker biostatistician with 9+ years of experience across academia and pharmaceutical clinical development, including 4+ years at Sanofi. Lead statistical contributor to Phase II/III clinical studies in immunology, with strong expertise in biomarker-driven analyses, longitudinal and survival models, and high-dimensional data. Experienced in regulatory submissions, clinical study reporting, and cross-functional collaboration to support clinical development and decision-making.

Biomarker Biostatistician at Sanofi (2022-05 – Present)

Lead biomarker statistical support and strategic delivery across clinical studies

• Lead biomarker statistical support across 12+ Phase II/III clinical studies in atopic dermatitis
• Provide statistical leadership for biomarker analysis planning including Statistical Analysis Plans
• Contributed to biomarker evidence supporting key clinical and regulatory decision-making
• Drive end-to-end biomarker strategy and delivery across Clinical Study Reports, regulatory filings, and scientific dissemination
• Partner with cross-functional teams across clinical, translational medicine, programming, data management, and medical writing
• Contribute to cross-study biomarker discussions and serve as a key contact for atopic dermatitis biomarker topics

Postdoctoral Research at Gustave Roussy, INSERM (2021-08 – 2022-04)

Methodological research in adaptive designs and survival analysis

• Contributed to methodological research in adaptive designs and survival analysis
• Worked on methods addressing non-proportional hazards and historical control settings

PhD in Biostatistics at Gustave Roussy, INSERM (2017-10 – 2021-07)

Developed statistical methods for biomarker identification in high-dimensional clinical trial data

• Developed statistical methods for biomarker identification in high-dimensional clinical trial data
• Applied penalized regression and survival models to oncology clinical trial datasets
• Conducted simulation studies and real-data applications, leading to peer-reviewed publications and international conference presentations

Biostatistician Intern at Gustave Roussy, INSERM (2017-02 – 2017-07)

Worked on bivariate survival modeling and surrogate endpoint validation

• Worked on bivariate survival modeling and surrogate endpoint validation using individual patient data meta-analysis
• Conducted simulation studies and applied methods to Phase III oncology trial data

PhD in Biostatistics – Université Paris-Saclay (2017 – 2021)

Engineering Degree in Statistics and Data Analysis – ESSAI (2013 – 2017)