Bioinformatics data analyst (Contract-full-time) - Mercor - Leeds (Remote)
(2025-01)
- Evaluated genomic and transcriptomic analysis outputs for biological accuracy.
- Reviewed protein structure predictions and functional annotations.
- Assessed experimental design and statistical interpretation in bioinformatics analyses.
- Identified errors in gene expression and pathway analysis reasoning.
- Performed quality control and validation of computational biology outputs.
Research Assistant - University of Leeds - Leeds, UK
(2024-01 - 2024-08)
- Investigated protein-protein interactions using 950 MHz Bruker NMR spectroscopy and SDS-PAGE to study conformational changes in IRE1-LD variants.
- Designed and executed in vitro functional assays to examine ATP-dependent oligomerisation with BiP.
- Purified labelled/unlabelled proteins via affinity chromatography and utilised AlphaFold for structural predictions.
- Developed Python and Excel visualisations to communicate experimental findings to interdisciplinary teams.
Bioinformatician – Fusion Protein Engineering - M.S. Ramaiah Institute of Technology - India
(2021-10 - 2022-07)
- Engineered a Cry1Da–Cry1B.867 fusion protein targeting Spodoptera frugiperda resistance using SWISS-MODEL homology modelling.
- Validated the model via Ramachandran plot (96.3% favoured regions) and performed molecular docking with APN/ABCB1 receptors using ClusPro.
- Conducted in silico toxicity and ADMET profiling (pkCSM), demonstrating a safe bio-profile for agrochemical discovery.
Bioinformatician – SNP Analysis in Parkinson's Disease - M.S. Ramaiah Institute of Technology - India
(2021-02 - 2021-10)
- Analyzed 286 missense SNPs in the PNMT gene using 17+ computational tools (PROVEAN, PolyPhen-2, PredictSNP, DynaMut, CUPSAT).
- Performed molecular dynamics simulations (GROMACS) to evaluate conformational changes (RMSD, RMSF, Rg, SASA) in mutant proteins.
- Identified 3 high-risk deleterious SNPs (L217Q, G79D, Y35D) proposed for wet-lab validation and therapeutic targeting.
- Developed a validated computational workflow for SNP prioritisation to support precision medicine pipelines.
Trial Coordination & Research Assistant - Stellixir Biotech - Bangalore, India
(2021-08 - 2022-02)
- Coordinated multi-site preclinical studies, ensuring protocol adherence and regulatory compliance.
- Performed cell culture and maintenance of cancer cell lines, including HCT116 (colorectal carcinoma), THP-1 (acute monocytic leukaemia) and Saos-2 (osteosarcoma)
- Performed MTT assays (96-well plates) and cytotoxicity evaluations.
- Maintained trial master files and prepared stakeholder reports.
Data Analyst (freelance) - Outlier - Leeds (Remote)
(2024-10 - 2025-09)
- Curated high-quality open datasets for biotech business intelligence, improving data usability by 25%
- Developed statistical models to inform research strategy and built Tableau dashboards tracking KPIs
AI Consultant (freelance) - Mindrift - Leeds (Remote)
(2025-09)
- Enhanced AI output accuracy and coherence by 20% through structured validation for biotech applications
- Applied prompt engineering to improve LLM performance in scientific communication
