Sheetal Surendra Vishwakarma

Led end-to-end bioinformatics analysis for 140+ projects spanning RNA-Seq, 16S rRNA, 18S rRNA, ITS, WGS, de novo assembly, sRNA, Shotgun and ChIP-Seq across diverse organisms. Served as primary analyst for clients from premier institutions including AIIMS, IISc, ICGEB, TIFR, and multiple IITs — managing full project lifecycle from raw data QC to final report delivery. Performed advanced downstream analysis including GSEA/topGO functional enrichment, gene network construction, PERMANOVA & PERMDISP, Aitchison PCoA, Differential abundance, Pathway enrichment and VCF calling & annotation and many such.

Scientist I - Computational Genomics - Chromosome Labs Pvt Ltd - Mumbai

(2025-09)

• Led end-to-end bioinformatics analysis for 140+ projects spanning RNA-Seq, 16S rRNA, 18S rRNA, ITS, WGS, de novo assembly, sRNA, Shotgun and ChIP-Seq across diverse organisms.
• Served as primary analyst for clients from premier institutions including AIIMS, IISc, ICGEB, TIFR, and multiple IITs — managing full project lifecycle from raw data QC to final report delivery.
• Performed advanced downstream analysis including GSEA/topGO functional enrichment, gene network construction, PERMANOVA & PERMDISP, Aitchison PCoA, Differential abundance, Pathway enrichment and VCF calling & annotation and many such.
• Developed and maintained reproducible workflows using Snakemake and Nextflow; contributed to pipeline standardization across the team.
• Developed end to end SLURM script for RNASeq, 16S and ITS pipeline.

Junior Scientist - miBiome Therapeutics LLP - Mumbai

(2024-09 - 2025-08)

• Independently executed 50+ RNA-Seq and 16S rRNA analysis projects for academic and industrial clients across India.
• Optimized NGS data analysis pipelines for improved throughput and reproducibility using R, Python, and Linux-based tools.
• Handled large-scale datasets, managing batch effects, sample QC, and statistical interpretation.

Bioinformatics Intern - miBiome Therapeutics LLP - Mumbai

(2024-03 - 2024-08)

• Implemented RNA-Seq and 16S (QIIME2) pipelines; supported senior analysts on active research projects.
• Conducted research and data analysis to compare microbiome community composition of identical samples processed with different companies' library preparation kits and primer sets.

Bioinformatics Intern - Epigeneres Biotech Pvt Ltd - Mumbai

(2023-08 - 2024-02)

• Performed mutation signature analysis using SigProfiler tools on transcriptome and exome datasets.
• Conducted RNA-Seq data processing using Linux-based pipelines, supported by systematic literature review.

R&D Intern (Biocuration) - Haystack Analytics Pvt Ltd - Mumbai

(2023-01 - 2023-02)

• Documented a comprehensive list of disease-associated genes; annotated corresponding gene mutations and curated biological research datasets for downstream computational use.

PG Diploma - Bioinformatics - St. Xavier's College (Autonomous) (2022-07 - 2023-05) Mumbai

BSc - Biotechnology - Sheth L.U.J College of Arts & Sir M.V College Of Science & Commerce, University of Mumbai (2019-06 - 2022-04) Mumbai