Siddique Khan

Professional Summary

• Name: Siddique Khan, PhD in Organic Chemistry from IIT Madras.
• Specialization: HDDA benzyne chemistry, halogenation and chalcogenation reaction development.
• Research: Designed novel trapping reactions and multi-step syntheses for complex aromatic scaffolds.
• Publications: First-author papers in Organic Letters and Chemistry — A European Journal.
• Techniques: Schlenk techniques, microwave-assisted synthesis, chromatography, crystallization.
• Characterization: 1H/13C NMR, HRMS/LC-MS, IR, UV-Vis, elemental analysis.
• Skills: Mechanistic insight, reaction optimization, rigorous lab documentation, EHS compliance.
• Teaching: Experience as TA for organic chemistry lab and mentoring junior researchers.
• Awards: DST INSPIRE fellowships and university gold medalist in M.Sc.
• Objective: Apply synthetic expertise to discovery or R&D roles in medicinal chemistry or process development.

• Multi-step synthesis of small molecules and aromatic frameworks
• BuLi, DIBAL, Grignard, LDA Reactions, Functionalization
• Green synthetic methodologies and solvent-free protocols
• Handling air/moisture sensitive reactions under inert atmosphere (Schlenk techniques)
• Column chromatography, TLC, crystallization, microwave-assisted synthesis
• Reaction monitoring via NMR, HPLC, TLC, UV-Vis
• Mass spectrometry (HRMS, LC-MS)
• Elemental and melting point analysis
• Mechanistic insight and structure-reactivity analysis
• Strong lab documentation and safety practices
• Efficient literature mining (SciFinder, Reaxys, PubMed)
• ChemDraw, Origin, MestReNova
• Gaussian (basic)
• LaTeX, Microsoft Office
• Teaching Assistant – Organic Chemistry Lab, B.Tech., IIT Madras (Jan–May 2020, Jul–Nov 2020, 2021)

Ph.D. in Organic Chemistry from IIT Madras with specialized expertise in hexadehydro-Diels–Alder (HDDA) benzyne chemistry, halogenation/chalcogenation, reaction. My doctoral research centered on designing novel trapping reactions within the HDDA cascade, enabling the development of halogenation and chalcogenation strategies for the construction of structurally complex aromatic systems. I am driven by a strong interest in chemical reactivity and stereoselectivity, aiming to translate mechanistic understanding into innovative synthetic approaches.

I have authored publications in peer reviewed journals such as Organic Letters, Chemistry - A European Journal and Chemical Record bring comprehensive experience in synthesis, mechanistic analysis, teaching, and scientific communication.