Host-pathogen interactions High throughout drug screening (HTS)
Drug repositioning/repurposing
Novel Anti-virulent drug screening
Biomarker assays
In-vitro drug validation Animal infection models
In-vivo drug efficacy studies In-vivo pharmacological studies
Drug toxicity testing
Pharmacological analysis of drug-immune interactions
경력
Exploring host pathogen interactions and human diseases by genome wide next generation dual RNA sequencing (
Multiomics based target identification for next generation antimicrobial and anti virulent therapies
High throughput screening of plant derived compounds and FDA approved drug libraries targeting global regulators to develop novel anti virulent drugs against multi drug resistant bacteria
Understanding the anti virulent immune interaction and their synergy to treat bacterial infections
Development of various animal infection models including MDR S aureus induced infective endocarditis, dermonecrosis and sepsis
Evaluation of small molecule inhibitors and its derivatization
Combinatorial approach to sensitize the multiple drug resistant bacteria against existing antibiotics
