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Jamie Lo

Jamie Lo

Researcher, Diagnostic Assays and Analytical Development

Talento
San Francisco, CAMiembro desde 11 de mayo de 2026
Assay developmentAssay design and executionLigand-bindingEnzymaticEnzyme potencyLuciferaseddPCRDNA/RNA isolationCell passagingAseptic techniquePrimer designAntibody conjugationSDS-PAGEWestern blotDesign of Experiments (DOE)Verification and Validation (V&V) testingData analysis and presentationTechnical writingRoot-cause analysisProtein expressionChemical formulationJMPGraphPad PrismSnapGeneLIMSMS Office SuiteRoche CobasUV-Vis Spectrophotometer
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Assay developmentAssay design and executionLigand-bindingEnzymaticEnzyme potency

Sobre mí

Detail-oriented and results-driven scientist with 6 years of research experience in molecular biology and biochemistry, specializing in experimental design, data analysis, and assay development and execution. Demonstrated expertise in cell culture, method development, technical writing, and sample organization.

Experiencia

Scientist at VMRD Diagnostics, Zoetis (2023-08 – 2025-05)

  • Contributed to the development of a multiplex point-of-care diagnostic assay project from the conceptualization and proof of concept, through Alpha verification and into Beta validation.
  • Applied Design of Experiments (DOE) methodologies to systematically optimize assay conditions, ensuring robust performance with consideration to consumable design, leading to seamless system integration.
  • Performed statistical analysis and interpretation of complex assay datasets using relevant tools to generate regulatory-compliant data packages and support validation under cGMP standards.
  • Co-authored and reviewed SOPs, study reports, and documentation for USDA submissions.

Research Associate I, Assay Science at BioMarin (2021-08 – 2023-07)

  • Performed routine and non-routine molecular testing procedures, including but not limited to vg titer determination and residual DNA levels of gene therapy products using ddPCR
  • Participated in the iterative development of residual plasmid assays and automatic mRNA extraction methods
  • Passaged and maintained in healthy condition a variety of cell lines, including C2C12, HepG2, and HepG2 KO
  • Conducted MyBPC3 transductions and potency assessments via luciferase assays
  • Carried out transgene PAH protein potency assays and field inversion gel electrophoresis for bacmid stability

Staff Research Associate II at Isacoff Lab, University of California, Berkeley (2019-09 – 2021-06)

  • Studied extent of visual restoration using behavioral assays such as novel object exploration and light aversion
  • Developed novel assays to detect visual function and optimized current assays
  • Conducted dosing, pharmacokinetic, and efficacy studies

Student Research Associate at University of California, Davis (2014 – 2018)

  • Extracted, purified, and separated proteins in concentration determination testing, applying polymerase chain reaction (PCR), enzyme-linked immunosorbent assay (ELISA), and Western Blot methods
  • Analyzed protein and enzyme functions through immunohistochemistry, Western blotting, and binding assays
  • Studied and recorded tissue morphology, number of cells and localization of cell receptors using histological and immunohistological analyses

Educación

Master of Science in Pharmacology – University of California, Irvine (2020)

Bachelor of Science in Pharmaceutical Chemistry – University of California, Davis (2018)

Habilidades

ResearcherDiagnostic Assays and Analytical Development

Valoraciones