Mario Perez Medina

Oncology researcher with extensive experience in the bioinformatics analysis of next-generation sequencing (NGS) data. Specialized in integrating and analyzing genomic datasets from in-house experiments and public repositories to unravel the molecular mechanisms of cancer and the immune response in oncological contexts. Skilled in developing and applying advanced analytical pipelines, interpreting complex multi-omic datasets, and effectively communicating scientific findings to interdisciplinary teams.

Dedicated to driving innovation in cancer research through data-driven insights and collaborative approaches.

Research at Asociación para Evitar la Ceguera en México (APEC) (2024-06 – Present)

• Ensure ethical and legal compliance in the handling of samples and data.
• Support for Research Projects: Collaborate with researchers in the design and execution of experiments.
• Assist in the collection and analysis of experimental data obtained by Flowcytometry, Rnaseq, Exome, and WGS.
• Training and Development
• Perform molecular analysis techniques, such as PCR, electrophoresis, and DNA or RNA isolation
• Biobanking & Sample Management: Coordinated the collection, processing, and preservation of clinical tissue and liquid biopsy samples for downstream genomic applications.
• Clinical-Research Interface: Acted as the liaison between clinical teams and research staff, ensuring accurate clinical data annotation for experimental datasets.
• Implement and perform the optical mapping technique (Saphyr Bionano) and cytogenetics, including Structural Chromosome Variant Analysis in different types of tissues and samples.
• Generate and analyze sequencing data using the MGI platform, including genome, exome, RNA-seq, and Oncogenes Panels in FFPE Tissue and cfDNA
• Integration of public genomic data (TCGA, GEO, ENCODE) for comparative studies.
• Development of automated bioinformatics pipelines using tools such as Python, R, and Bash.
• Properly prepare samples for analysis, including preservation.
• Document experimental procedures and results in detail.
• Maintain accurate records of reagent and material inventories.
• Regulatory Compliance: Strictly follow safety protocols and biosafety regulations.
• Participate in training courses and workshops to stay updated with new laboratory techniques and technologies.
• Train new team members in the use of laboratory equipment and procedures.

Molecular Biology Analyst at Genelab (2023-08 – 2024-05)

• Implement and perform the optical mapping technique (Saphyr Bionano) and cytogenetics, including Structural Chromosome Variant Analysis in different types of tissues and samples.
• Generate and analyze sequencing data using the MGI platform, including genome, exome, RNA-seq, and Oncogenes Panels in FFPE Tissue and cfDNA
• Develop and execute comprehensive marketing strategies and campaigns that align with the company's goals and objectives.
• Integration of public genomic data (TCGA, GEO, ENCODE) for comparative studies.
• Development of automated bioinformatics pipelines using tools such as Python, R, and Bash.
• Properly prepare samples for analysis, including preservation.
• Document experimental procedures and results in detail.
• Maintain accurate records of reagent and material inventories.
• Regulatory Compliance: Strictly follow safety protocols and biosafety regulations.
• Participate in training courses and workshops to stay updated with new laboratory techniques and technologies.
• Train new team members in the use of laboratory equipment and procedures.

Research at Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas e Instituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas" (2010 – 2024)

My postgraduate studies were focused on Cancer Biology. I studied the mitochondrial dynamics and function in cancer cells, investigating how mitochondrial alterations contribute to cancer progression and resistance to therapy. Additionally, I performed sequencing to identify differential gene expression in drug-tolerant persister cells, aiming to uncover the molecular mechanisms underlying their survival and resistance to conventional treatments.

PhD in Biomedic and Molecular Biotechnologic Sciences in Biomedic and Molecular Biotechnologic Sciences – Escuela Nacional de Ciencias Biológicas-IPN (2018 – 2024)

Master in Biomedic and Molecular Biotechnologic Sciences in Biomedic and Molecular Biotechnologic Sciences – Escuela Nacional de Ciencias Biológicas-IPN (2015 – 2017)

Bachelor of Biology in Biology – Facultad de Estudios Superiores Iztacala, UNAM (2010 – 2014)