Matthew Jabro
Senior Thesis Researcher
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About
Independent Computational Biology & Genomics Research
Experience
Senior Thesis Researcher - Kravis Department of Integrated Sciences - Claremont, CA
(2024-08)
Independent Computational Biology & Genomics Research
- Designed and executed a large-scale soil microbiome analysis using global 16S rRNA datasets; built the full pipeline on a high-performance computing cluster from FASTQ preprocessing through classification.
- Implemented CLR transformation, mixture graphical model clustering, and Random Forest classification to predict habitat type from genus-level taxa abundance, integrating environmental metadata (soil pH, climate, geography).
- Made and defended independent analytical decisions on taxonomic cutoffs, inclusion thresholds, and feature filtering, each materially shaping downstream results.
Data Science Capstone (Team Lead) - Huntington Medical Research Institute - Claremont, CA
(2025-08 - 2025-12)
Machine Learning for Sleep Apnea Detection — CPAP Alternative Device
- Developed the full ML pipeline for a wearable prototype designed to prevent sleep apnea events through targeted stimulation, in direct collaboration with the clinical client team.
- Engineered features from raw physiological signals (spectrograms, Kalman filters) and benchmarked multiple classifiers, selecting gradient boosting based on validation performance.
- Generated ROC analyses and recommended operating thresholds the client used to evaluate false-positive vs. false-negative tradeoffs; presented final recommendations to the client team.
Clinical Research Assistant - Sharp Neonatal Research Institute - San Diego, CA
(2025-06 - 2025-08)
Neonatal Positive Pressure Ventilation (PPV) Outcomes Study
- Reviewed 100+ delivery room videos and extracted millisecond-level PPV start/stop timestamps across multiple ventilation intervals per case.
- Linked timing data to clinical outcomes (length of stay, survival) using Cerner to cross-reference physician notes, demographics, and patient records.
Independent Researcher - Scripps College & Youngstown State University - Claremont, CA & Youngstown, OH
(2023-02 - 2024-08)
Non-Invasive Hemoglobin Detection Device (with Profs. Landsberg & Crescimanno)
- Initiated and led an independent project to detect hemoglobin changes non-invasively using the paramagnetic properties of iron in heme.
- Built and tested a working prototype with graduate collaborators; identified a hardware-imposed signal-resolution ceiling tied to magnet strength.
Clinical Neurology Intern - Pacific Neuroscience Institute
(2024-05 - 2024-07)
- 320 hours supporting hydrocephalus and multiple sclerosis clinics; gathered patient histories, reviewed MRI neuroimaging with physicians, and observed neurosurgical tumor resections.
- Completed a structured cadaver lab led by a neurosurgery fellow (suturing, instrument handling).
Hospital Volunteer - Pomona Valley Hospital and Medical Center
(2024-09)
- 150+ hours of direct patient-care support during discharge and care transitions; coordinated with nursing staff for safe wheelchair transfer of post-discharge patients.
Lab TA, Intro Biology & Computer Science (SCI 10 / SCI 50) - Kravis Dept. of Integrated Sciences
(2024-01 - 2025-12)
- 100+ hours supporting wet- and dry-lab sessions; troubleshot student Python code and ran supplementary experiments to generate teaching data.
Organic Chemistry Tutor - Scripps-Pitzer Science Center
(2024-08 - 2025-05)
- Department-sponsored 1-on-1 tutoring focused on problem-solving fluency over rote recall.
Team Representative - CMC Student-Athletic Advisory Committee (SAAC)
(2024-09)
- Voted on department policy and resource allocation across two academic years.
Education
Bachelor of Arts - Data Science - Claremont McKenna College
