Matthew Nagy

Pediatrician trained at Boston Children's Hospital (Boston Combined Residency Program, 2026), practicing primary care and hospital medicine in Boston. Builds and evaluates digital tools for children and families, drawing on seven years of pediatric AI work: intensive care prediction models, the JAMA Pediatrics analysis of FDA-authorized AI devices and frontier-model safety evaluation. Trained in public and global health (MPH; Uganda and Burundi).

Author of 33 peer-reviewed publications, including papers in the New England Journal of Medicine, Nature Communications, Cancer Cell, Cancer and JAMA Pediatrics.

Primary Care Pediatrician - West Cambridge Pediatrics and Adolescent Medicine - Cambridge, MA

(2026-07)

• Deliver comprehensive primary care to infants, children, and adolescents, including preventive and well-child care, acute illness, and chronic condition management.
• Build a continuity panel and long-term relationships with families.

Per Diem Hospitalist - Boston Children's Hospital - Boston, MA

(2026-09)

• Provide inpatient pediatric care on a flexible per diem schedule at a Harvard-affiliated children's hospital, joining established teams on shift to manage acute illness and clinical uncertainty.

Per Diem Urgent Care Pediatrician - Atrius Health - Norwood, MA

(2026-12)

Physician Expert, Medical AI Evaluation (contract) - AfterQuery - Remote

(2026)

• Write pediatric clinical scenarios and grading rubrics that expose failures in frontier medical AI models.
• Selected as one of 20 high-performing physicians for additional evaluation projects.

Researcher, Computational Health Informatics Program - Boston Children's Hospital and Harvard Medical School - Boston, MA

(2024 - 2024)

• Co-authored a JAMA Pediatrics review of 876 FDA-authorized AI-enabled medical devices; only 17% were labeled for children, and only 19% of those reported using pediatric data.
• Findings covered by Boston Children's Hospital and Becker's Hospital Review.

Medical Student Researcher; Principal Investigators: Orkun Baloglu, MD and Aziz Nazha, MD - Cleveland Clinic, Center for Clinical Artificial Intelligence - Cleveland, OH

(2019 - 2023)

• Developed pediatric-trained machine learning models to predict mortality and acute kidney injury in the pediatric intensive care unit (Critical Care Explorations, 2021; Pediatric Nephrology, 2024); presented the kidney injury model as an oral presentation at the American Academy of Pediatrics National Conference (2022).
• Co-developed a curriculum to teach medical trainees the fundamentals of machine learning, including a pilot remote curriculum for residents and medical students (World Neurosurgery, 2023).
• Drafted narratives on the role of machine learning in oncology and hematology, and commentaries on its role in medical education and the doctor–patient relationship (JCO Clinical Cancer Informatics; The Lancet Haematology; AMA Journal of Ethics; Medical Science Educator).

Researcher; Principal Investigator: Katherine A. Janeway, MD, MMSc - Dana-Farber Cancer Institute / Boston Children's Hospital / Harvard Medical School

(2024)

Project: Roles of Somatic Genomic Alterations in Pediatric and Young Adult Osteosarcoma

• Analyze targeted panel sequencing data from patients with high-risk osteosarcoma to identify clinically impactful somatic variants.
• As first author, showed that MYC amplification and MYC protein expression are poor prognostic markers in pediatric and young adult osteosarcoma (Cancer, 2025; presented at the American Society of Clinical Oncology Annual Meeting).

Researcher; Principal Investigator: Riaz Gillani, MD - Broad Institute of MIT and Harvard / Dana-Farber Cancer Institute / Boston Children's Hospital

(2024)

Project: Exploring the Germline of Early Onset Pediatric Cancers

• Interrogate whole-genome sequencing data through variant calling, annotation, filtering, and visualization in the Integrative Genomics Viewer, integrated with clinical data, to identify candidate cancer predisposition genes.
• As first author, reported novel germline risk factors in early-onset pediatric solid tumors (JCO Precision Oncology, 2026).

Researcher; Principal Investigators: Eytan Ruppin, MD, PhD (NIH) and Stefan Pfister, MD (Kitz-Heidelberg) - Cancer Data Science Laboratory, National Cancer Institute, National Institutes of Health

(2021)

Project: Identifying Synthetic Lethal Partners for Pediatric Cancers as Precision Therapy Targets

• Mine multiomic databases, including TARGET and INFORM, to identify synthetic lethal gene targets in pediatric tumors as candidates for precision therapy.
• Apply computational deconvolution to bulk RNA sequencing data to uncover potentially vulnerable cell–cell interactions in pediatric solid tumors.
• Contributed as an equal-contribution co-author to a New England Journal of Medicine report of response to PARP inhibition in BARD1-mutated refractory neuroblastoma (2024); presented synthetic lethality findings at the American Association for Cancer Research (2023) and Advances in Neuroblastoma Research (2023) meetings.

Researcher; Principal Investigator: Sahera Dirajlal-Fargo, DO - Case Western Reserve University and Makerere University - Kampala, Uganda

(2019-12 - 2023-04)

Project: Evaluating the Relationship between Pediatric HIV, Air Pollution, and Cardiovascular Disease in Ugandan Adolescents

• Performed geospatial and longitudinal cohort analyses of how elevated air pollution contributes to the development of cardiovascular disease among adolescents in Kampala, Uganda.
• As co-first author, helped show that ambient air pollution is associated with vascular disease in Ugandan adolescents with HIV (AIDS, 2022); the work was selected among the top 4% of abstracts at the Consortium of Universities for Global Health conference.

Researcher; Principal Investigator: Eric McLaughlin, MD - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2017-06)

Project: Developing and Evaluating a Sustainable Intervention to Decrease Infant and Maternal Mortality in Rural Burundi (Zigama Mama)

• Evaluated an intervention that offers mothers at high risk of delivery complications an ultrasound evaluation and the choice between a scheduled C-section and a supervised trial of vaginal delivery in the hospital.
• Led statistical analyses of program outcomes and designed an infographic that communicated the findings to local health leaders; results published in Frontiers in Global Women's Health (2023).

Researcher; Principal Investigator: Alyssa Pfister, MD - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2017-06)

Project: Evaluating the Effectiveness of an Outpatient Pediatric Malnutrition Program in Rural Burundi

• Evaluated one-year weight gain by frequency of attendance in an outpatient program that provides Burundian children with Busoma (a soy-and-maize porridge) and nutrition education.
• Collaborated with local health care workers to develop a Kirundi-language survey, tailored to the local context, assessing parent demographics, distance traveled, and perceptions of the program.

Researcher; Principal Investigator: Rebecca Hasson, PhD - Childhood Disparities Research Laboratory, University of Michigan

(2013 - 2018)

Project: Active Class Space Study

• Contributed to a laboratory-based clinical trial examining the metabolic, psychological, and cognitive responses of elementary school–age children to intermittent physical activity at various intensities.
• Translated findings into a school-based intervention, evaluated its feasibility and efficacy, and implemented it in schools throughout Michigan.
• Lab work resulted in multiple peer-reviewed publications, including first-author papers in Journal of Physical Activity and Health, Psychosomatic Medicine, and Journal of Asthma.

Resident Physician - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2026-01 - 2026-02)

• Rounded on and cared for children admitted to the inpatient general pediatric, malnutrition, and neonatology wards.
• Mentored local medical students on clinical rounds and in the development and evaluation of their thesis research.

Program Analyst - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2017)

• Support clinical innovation through formal statistical evaluation of quality improvement initiatives, resulting in national presentations and peer-reviewed publication.

Medical Student Rotator - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2022-09 - 2022-09)

• Rotated through the pediatric ward and developed an introductory statistics curriculum to prepare Burundian medical students at Kibuye Hope Hospital for their required thesis work.

Public Health Intern - Kibuye Hope Hospital, Hope Africa University - Kibuye, Burundi

(2017-06 - 2017-08)

• Alongside program evaluation (see Additional Research Experience), developed infographics and educational materials for patients and providers, engaged in play therapy with children on the pediatric wards, and organized crafts and activities for children of hospital staff.

Executive Director - Opportunities to Educate Children, University of Michigan - Ann Arbor, MI

(2015 - 2017)

• Led a board of five directors and 70+ tutors serving Ann Arbor schools, community centers, and hospitals.
• Awarded $11,000 for program expansion by the Optimize Social Innovation Challenge and United Way Washtenaw County.

Hospital Tutoring Director - Opportunities to Educate Children, University of Michigan - Ann Arbor, MI

(2014 - 2015)

• Facilitated growth of the program and initiated new tutoring programs on the Pediatric Oncology and Pediatric General Care floors at Mott Children's Hospital.

Academic Tutor for Pediatric Oncology and Pediatric Dialysis Patients - Opportunities to Educate Children, University of Michigan - Ann Arbor, MI

(2014 - 2018)

Volunteer Coordinator - Camp Quality Michigan, Camp Quality USA

(2015 - 2018)

• Recruited, background-checked, interviewed, and trained 80+ volunteers each year to staff a free week of camp for children with cancer.

Companion - Camp Quality Michigan, Camp Quality USA

(2014)

• Serve as a one-on-one counselor to the same camper year to year and take part in events with the family throughout the year.

Medical Student District V Representative (Michigan, Ohio, Indiana, Illinois, Toronto) - American Academy of Pediatrics

(2021 - 2022)

Assistant Medical Student District V Representative - American Academy of Pediatrics

(2020 - 2021)

Medical Student Delegate - Cleveland Clinic Lerner College of Medicine

(2019 - 2021)

Internship and Residency in Pediatrics - Global Health Track - Boston Combined Residency Program (2023-06 - 2026-06)

Doctor of Medicine - Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (2018-06 - 2023-05)

Master of Public Health - Health Behavior and Health Education - University of Michigan School of Public Health (2016-08 - 2018-05)

Bachelor of Science - Movement Science, Honors Program, summa cum laude - University of Michigan, School of Kinesiology (2013-08 - 2017-05)