Ramkrishna Sadhukhan
Senior Principal Research Scientist (Director)
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About
Scientist. Strategist. Builder of biologics platforms that move the needle in therapeutic innovation.
I’m a passionate leader in therapeutic protein engineering and genetic medicine, bringing two decades of experience across AbbVie, Vertex, and Abbott Labs. I lead cross-functional teams and drive programs from concept to candidate—spanning monoclonal and bispecific antibodies, fusion proteins, mRNA modification, and LNP formulation, mRNA-LNP conjugation.
My work bridges scientific rigor with strategic thinking: I’ve led due diligence for multimodal assets, designed cutting-edge biologics platforms, and forged academic-industry partnerships that accelerate discovery. From building scalable expression systems to co-leading high-profile biologics and mRNA programs, I thrive in unlocking breakthrough therapies and mentoring the next generation of scientific innovators.
Always open to collaborations that shape the future of biologics, genetic medicine, and personalized therapeutics.
Experience
- mRNA modification, LNP formulation,
- mRNA-LNP conjugation and targeted gene delivery
- Bispecific antibody engineering (DVD-Ig, KiH)
- Fusion protein engineering
- Cell line & expression system development
- Asset due diligence & CRO collaboration strategy
- Structural biology supports small molecule platforms
- Cross-functional team leadership in matrixed environments
Education
PHD in Biochemistry, specialized in therapeutic Protein Engineering, Targeted mRNA delivery for gene therapy.
