Sabine Ackerknecht

I am a passionate and highly reliable scientist with 17 years of experience in oncology, immuno-oncology and toxicology. With my experience in cellular and biochemical assay development and SAR profiling, I would like to contribute finding new starting points for drug discovery.

Senior Scientific Associate- Oncology

Idorsia Pharmaceuticals: Jul 2017-Dez 2023

Establish, validate and perform biomarker assays for drug screening and mode of action (MoA) assessment in cell lines and samples of mouse models; set-up of flow cytometry and human NK and T cell killing assays; spheroids;

Research Associate- Oncology

Actelion Pharmaceuticals Ltd.: Feb 2010-Jul 2017

Develop, validate and apply cellular and enzymatic assays for target validation and HTS compound screening; FP Assay and phenotypic screen to study Hsp70 inhibitors; set-up of a high content imaging EMT-screen; leadership of apprentice, trainees and co-workers.

Scientific Associate II- Investigative Toxicology

Novartis AG: Aug 2006-Feb 2010

Development of primary cell culture models for steatosis and cholestasis and their analysis with the high content multi-parameter system of Cellomics.

Biology Lab Assistant

Altana Pharma AG: Aug 2001-Okt 2002

Set-up and evaluation of a cytokine-driven T-cell proliferation assay.

Dipl. Ing. Environmental- and Process Engineering focus Biotechnology

Bachelor of Engineering Biotechnology

University of Applied Sciences Furtwangen; Sep 2002-Feb 2008