Kakularam Kumar reddy
Bioinformatician/Research Scientist
Talente
Berlin, BerlinMitglied seit 18. April 2023
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Über
- A post-doctoral fellow with 12 years of research experience 21 publications in peer-reviewed scientific journals, and a patent on drug discovery
- Expertise in bioinformatics methods such as computer-aided drug design, protein structural analysis, whole genome data analysis, etc.
- Experience with recombinant protein expression and purification, structural characterization and evaluation of proteins, inhibitor assays, HPLC-based analysis of lipid mediators, etc.
- Proficiency with python, machine learning, and deep learning
Berufserfahrung
- Research Scientist (July 2019-July 2022) - Institute of Biochemistry, Charité, Berlin, Germany
- Analyzed whole genome sequence data and gene databases and extracted the gene sequences from more than 150 animals for protein characterization studies
- Evaluated the specificity and efficiency of 13 inhibitors against 8 enzymes from human and mouse lipoxygenase family
- Investigated the catalytic/enzymatic properties of multiple enzymes from the lipoxygenase family
- Post-doctoral Fellow (September 2017 – July 2019)- University of Hyderabad, Hyderabad, India
- Screened more than 100 inhibitors against 12R-Lipoxygenase enzyme and developed a novel drug candidate
- Received a patent for the development of a novel drug candidate
- Optimized protein expression and system and developed an inhibitory assay for drug development
- Applied computer-aided drug design methods and identified promising inhibitors against lipoxygenases
Ausbildung
- Coding Bootcamp for Data Science and Machine Learning (2022) - Lewagon, Berlin, Germany
- PhD-Lifesciences (2010-2017), University of Hyderabad, Hyderabad, India
