Assistant General Manager - Endoc Biotech Pvt. Ltd.
(2023-02)
Biotech company working in fermentation based API. Technical Head involved in broad range of activities.
- Product selection, development. Validation at lab scale and plant scale
- Plant design, QMS, Technology transfer, Plant Validation and DMF preparation of API
- Supply chain and Vendor qualification
- Active member in FDCA, GMP and WHO audit
- Mupirocin: Plant validation, WHO approval and CEP filing
- Mupirocin Calcium: Plant Validation
- Tacrolimus: Plant validation
- Fusidic acid: Plant validation
- Cyclosporine: Lab validation and pilot scale up
Asst. Manager - Intas Pharmaceuticals Limited
(2021-10 - 2023-02)
Involved in isolation of Tacrolimus crude and purification of crude.
- Literature survey and proposal of synthetic route/isolation for API
- Feasibility, optimization, validation and technology transfer of API
- Preparation or isolation, purification and characterization of impurity of API
- Preparation of Development report and Technology transfer document
Sr. Executive - Concord Biotech Limited
(2016-01 - 2021-09)
Biotech company working in semi synthesis and fermentation based API.
- Down streaming: DoxorubicinHCl, Amphotericin-B, Sirolimus
- Semi synthesis: Everolimus, Everolimus with 2% BHT, Everolimus premix, Biolimus, Doxorubicin HCl, Epirubicin HCl
- Literature survey and proposal of synthetic route/isolation for API
- Synthesis, development, optimization, validation and technology transfer of API
- Preparation or isolation and characterization of respected impurity of API
- Preparation of Technology transfer document
Entrepreneurship - Sigma Energy
(2012-01 - 2015-12)
Basic research division working on Chemicals and Nanotechnology.
- Development, optimization, validation and technology transfer of product as per customer's requirement
- Synthesis and isolation of metal, metal oxide and mixed metal oxide nanoparticle with organic compound capping
- Characterization of nanoparticle in terms of particle size, morphology and XRD
- Preparation of nano suspension in aqueous, polar and non-polar solvents for the solar cell and other relevant application
Research Scientist - Alembic Research Center
(2009-09 - 2011-12)
API Division.
- Handling of API projects, Scale up of R & D batches to commercial scale, Process Optimization, Characterization, Process development of products and Patent evaluation
- Vendors selection of Key Raw materials, Process validation and Commercialization, PDR & TTD preparation
- Coordinate with IPR, ADL and their team for development activity
- Technology transfer of DuloxetineHCl API
- Synthesis and development of Montelukast Sodium API and its respected impurities
- Literature survey, Synthesis, development and technology transfer of Dronedarone HCl API and its respected impurities
Junior Technical Supervisor - Cadila Pharmaceutical Ltd
(2004-04 - 2005-09)
API Division.
- Development of API and scale up activities
- Synthesis, development and technology transfer of Fexofenadine HCl API
- Synthesis of Carbetapentane tannate API
- Synthesis of Levetiracetam
R&D Chemist - Uma Laboratories Ltd.
(2003-07 - 2004-03)
Contract Research Organization.
- Synthesis of ethers and some heterocyclic moieties of drugs
- Synthesized many types of ethers with Williamson synthesis
- Handled successfully Milligram to Gram scale reactions
