Seonghun YOON, PhD

Research Assistant

Talent

NY, New YorkMember since October 4, 2026

myocardial infarction (MI)ischemia/reperfusion (I/R)Neonatal MItransverse aortic constriction (TAC)pulmonary artery banding (PAB)left stellate ganglion ablation (LSA) + TACintramyocardial injection (IMCI into LV or RV wall)PV-loop and IVC occlusionMillar-probe pressure gradientstelemetry (HR/BP, LVSP, ECG)flow probescannulation/catheterization (carotid, femoral, jugular, aorta, LV)microsphere studiesechocardiographytail-cuff BPmiddle cerebral artery occlusion (MCAO)subarachnoid hemorrhage (cranial window, cisterna magna puncture)5/6 nephrectomyhindlimb ischemiaosmotic-pump implantationjugular-vein catheterization/vascular access button (JVCB)In Vivo Imaging System (IVIS)organoid implants under the kidney capsuletumor inoculation modelsCardiac instrumentation (flow probes, occludes for LAD, crystals, aortic/atrial TTC stainingheart perfusioninfarct scanning and quantification (ImageJ)isometric-tension organ-bath studiesMouse (extensive transgenic and knockout lines)

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myocardial infarction (MI)ischemia/reperfusion (I/R)Neonatal MItransverse aortic constriction (TAC)pulmonary artery banding (PAB)

About

Cardiovascular research scientist and small-animal microsurgeon with more than three decades of biomedical research experience, including 16 years specializing in preclinical heart failure models.

Currently Core

Director of the Small Animal Surgery Core at the Cardiovascular Research Institute (CVRI), Icahn School of Medicine at Mount Sinai, where I lead high-throughput, highly reproducible microsurgery, develop and troubleshoot new surgical procedures, and train a surgical fellow and laboratory staffs. Author of 29 peer-reviewed publications, including work in Nature, Circulation, and Immunity. Established expertise in cardiac ischemia and heart failure, cerebrovascular, and renal disease models across mice (including numerous transgenic lines), rats, rabbits, and large-animal species.

Experience

Research Assistant - ChungAng University - Seoul, South Korea

(1989-03 - 1991-02)

Researcher - National Institute of Safety Research - Seoul, South Korea

(1991-03 - 1991-12)

Research Scientist - Boryung Pharmaceutical Co. - Gyeonggi-do, Korea

(1992-01 - 1993-02)

PhD graduate - ChungAng University - Gyeonggi-do, Korea

(1992-03 - 1995-02)

Research Scientist - Choongwae Pharmaceutical Co. - South Korea

(1995-03 - 1999-03)

Research Associate - Dr. Robert M. Rapoport Lab, Dept. of Pharmacology & Biophysics, University of Cincinnati

(1997-03 - 2010-05)

Trainee for the LAD ligation and Open-Chest surgery - Dr. Muhammad Ashraf's Lab, Cardiovascular Center, University of Cincinnati

(2010-06 - 2010-08)

Research Scientist (Rodent Heart Failure Microsurgeon) - Dr. Stephen F. Vatner Lab, Dept. of Cell Biology & Molecular Medicine, New Jersey Medical School, Rutgers University

(2010-09 - 2020-11)

Senior Scientist (Rodent Heart Failure Microsurgeon) - Dr. Lior Zangi Lab, Icahn School of Medicine at Mount Sinai

(2020-11 - 2022-06)

Senior Scientist (Lead Microsurgeon) & Core Director of Small Animal Surgery Core - Cardiovascular Research Institute (CVRI), Icahn School of Medicine at Mount Sinai

(2022-07)

Assistant Professor (pending) - Department of Medicine, Division of Cardiology, Icahn School of Medicine at Mount Sinai - NY, New York

(2026-09-01)